MS
World map | |||||||||||
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MS
UK map numbers per 100,000 | |||||||||||
| |||||||||||
(Numbers per 100,000) England
and Wales | |||||||||||
| 87
– 112 66 138 134 – 287 21 – 37 75 – 132 134 112 66 98 52 105 85 - 108 110 22 – 44 94 74 28 – 85 94 88 45 77 97 32 – 79 32 – 76 50 45 – 61 144 – 152 4 83 28 – 40 27 – 42 30 – 43 16 10 46 46 46 25 – 55 90 46 4 8 5 30 13 12 – 41 1 1 1 1 – 4 4 – 8 10 10 29 – 80 6 – 15 13 4 3 11 81 | |||||||||||
| UK: ......... ......... 85,000 N. & S: 3,800 12,000 6,000 ? W. & S: 5,000 285 110,000 ? 7,000 15,000 8,900 50,000 400 50,000 W. & N: 30,000 10,000 6,600 30,000 5,000 ? ? ? ? ? 7,500 3,200 ? ? 5,000 350 30,000 ? 35,000 250,000 7,000 8,000 ? ? 5,000 ? ? ? 50 5,000 ? ? 290 4,500 ? over all: .......... 1,500 12,000 3,000 | |||||||||||
The main message from this examination of worldwide MS prevalence is the impact of genetic factors on the development of the condition. MS is rare in certain ethnic populations (China, Japan, African blacks). Higher risks of MS in other populations (Sardinia, Scotland, African whites when compared to Afrikaners), suggests that different ethnic groups have differing levels of susceptibility. These differences may partly explain the uneven geographic distribution of the condition. The geography of MS might therefore be explained by the distribution of genetic susceptibility, which is then modified and influenced by factors in the environment. | |||||||||||